UK Clinical Pharmacy Association

Carbocisteine

Issues for surgery

Possible increase in sputum viscosity in patients with bronchiectasis and chronic obstructive pulmonary disease (COPD) if omitted.

Advice in the perioperative period

Elective and emergency surgery 

Continue.

Post-operative advice

If patient nil-by-mouth post-operatively consider alternative mucolytics e.g. nebulised sodium chloride.

Interactions with common anaesthetic agents

None.

Interactions with other common medicines used in the perioperative period

None.

Further information

None.

References

Joint Formulary Committee. British National Formulary (online) London: BMJ Group and Pharmaceutical Press. http://www.medicinescomplete.com [Accessed on 5th November 2020]

Summary of Product Characteristics – Mucodyne® (carbocisteine) 375mg Capsules. SANOFI. Accessed via www.medicines.org.uk 05/11/2020 [date of revision of the text March 2020]

Baxter K, Preston CL (eds), Stockley’s Drug Interactions (online) London: Pharmaceutical Press. http://www.medicinescomplete.com [Accessed on 5th November 2020]