Issues for surgery
For irritable bowel syndrome, smooth muscle spasm, dysmenorrhoea – loss of symptomatic relief if omitted.
Advice in the perioperative period
Elective and emergency surgery
Continue.
Except:
- Fybogel® mebeverine (ispaghula + mebeverine) - see Ispaghula husk monograph
Post-operative advice
Resume post-operatively, if needed, once enteral intake resumed.
Review mebeverine if patient develops reduced gastrointestinal motility (e.g. ileus) post-operatively.
Interactions with common anaesthetic agents
None.
Interactions with other common medicines used in the perioperative period
None.
Further information
None relevant.
References
Baxter K, Preston CL (eds), Stockley’s Drug Interactions (online) London: Pharmaceutical Press.
Joint Formulary Committee. British National Formulary (online) London: BMJ Group and Pharmaceutical Press. http://www.medicinescomplete.com [Accessed on 7th March 2021]
Summary of Product Characteristics – Mebeverine 135mg film-coated tablets. Aurobindo Pharma-Milpharm Ltd. Accessed via www.medicines.org.uk 07/03/2021 [date of revision of the text October 2020]