UK Clinical Pharmacy Association


Issues for surgery

For supplementation, or treatment, of vitamin B deficiency – risk of deficiency if omitted for prolonged period.

For treatment, or prophylaxis, of neuropathy secondary to isoniazid or penicillamine – risk of neuropathy if omitted.

Advice in the perioperative period

Elective and emergency surgery 


Post-operative advice

Restart at patient’s usual dose once enteral intake resumes.

Interactions with common anaesthetic agents


Interactions with other common medicines used in the perioperative period


Further information

None relevant.


Joint Formulary Committee. British National Formulary (online) London: BMJ Group and Pharmaceutical Press. [Accessed on 16th September 2023]

Summary of Product Characteristics – Pyridoxine 10mg Tablets. Tor Generics Limited. Accessed via 16/09/2023 [date of revision of the text April 2018]

Baxter K, Preston CL (eds), Stockley’s Drug Interactions (online) London: Pharmaceutical Press. [Accessed on 16th September 2023]